What does it mean to have a hangover? What are some of the symptoms you may experience when you wake up after an all-night drinking binge, and why is this such a huge problem for those who use modafinil (trade name Alertec) or Provigil (Modalert)?

Modafinil is a drug that has been used for years as a treatment for sleep disorders. It’s also been known to be used as a performance-enhancing drug. But, what about the hangover? What you need to know is that modafinil can cause severe side effects and hangovers.

Modafinil and Hangovers | What You MUST Know

Who’d have guessed that Modafinil and hangovers would go well together?

We already know that combining Modafinil with alcohol isn’t the best idea in the world. A stimulant and a depression acting in opposition to one another is a prescription for catastrophe.

Not to mention the various Modafinil adverse effects that are exacerbated by excessive alcohol use.

The majority of people are unaware that a “Modafinil hangover treatment” exists. With 100-200 mg of Modafinil and some common sense, you can cure a terrible hangover.

You may keep your productivity from sinking by combining the advantages of this smart medicine against a hangover. You’ll be able to do the most crucial tasks as if it were any other day.

Instead than feeling like you’ve died from drinking, you’ll have better concentration and more vitality.

With Modafinil on your side, there’s no way you won’t get things done.


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What exactly is Modafinil?

To assist you understand why Modafinil has the potential to be a hangover cure, let’s go over some basic information on it.

Despite its mechanism of action being quite different from psychostimulants like amphetamines, modafinil is classed as a central nervous system (CNS) stimulant.

The FDA has authorized it to treat three medical disorders that cause excessive daytime sleepiness:

  • Obstructive sleep apnea (OSA) is a kind of sleep apn
  • Shift work sleep disorder
  • Narcolepsy

Despite this, Modafinil has become one of the most potent smart medications in the world during the last two decades. It has various cognitive-enhancing benefits, including enhanced attention and the capacity to focus on one activity for extended periods of time.

So much so that its efficacy has been evaluated in healthy non-sleep deprived persons [2]:

“Modafinil consistently improved task pleasure and performance on multiple planning and working memory cognitive tests… The results show that modafinil can improve elements of high-demand cognitive function in people who aren’t sleep deprived.”

However, how does this lead to people associating Modafinil with hangovers?

Is there a Modafinil-alcohol interaction that prevents the noticeable declines in cognitive abilities that occur after a night of heavy drinking?



The Basics of Modafinil and Hangovers

Before we dive into a “Modafinil hangover cure,” it’s important to understand the science of feeling hungover.

When a person drinks too much alcohol, a hangover is described as the mental and psychological stress that results in unpleasant side effects. “Too much” is purely subjective, since everyone’s tolerance for alcohol is different.

Excessive alcohol consumption leads to the following outcomes, according to the Mayo Clinic [3]:

  • Irritates your stomach, which might explain post-hangover nausea and vomiting.
  • Blood sugar levels drop, which might explain physical weakness and emotional swings.
  • Reduces the quality of your sleep, leaving you exhausted when you wake up.
  • Makes you urinate more often, leading to dehydration.
  • Increases the size of your blood vessels, which might cause headaches.
  • Induces an inflammatory reaction in your immune system, further impairing your cognitive abilities.

A number of these side effects are caused by the liver being overworked in order to process 90% of the alcohol you consume [4]:

“The longer it takes to digest alcohol, the greater the blood alcohol concentration.” At any one moment, the liver can only metabolize a particular quantity of alcohol (roughly one drink per hour).

When someone drinks too much, the alcohol that the liver does not metabolize circulates through the bloodstream. People get inebriated when the alcohol in their blood begins to influence their heart and brain.”

The harmful effects of hangovers on one’s cognitive function are the major reason why heavy drinkers look for a hangover cure. As a result, the aim is to find a method that quickly restores your mental capacity to pre-alcohol levels.

Modafinil has previously been used to treat hangovers among Wall Street executives. It seems to boost alertness, focus, and memory in the morning after a night of drinking based only on anecdotal experiences [5].

This is due to Modafiniml’s shown potential to relieve tiredness in those with depression, severe sleep deprivation, and multiple sclerosis [6].

Some research show that Modafinil may aid alcoholics in reducing their impulsivity and, as a result, lowering their alcohol intake [7].

So, how can Modafinil be employed as part of a reliable hangover recovery strategy?



How to Use Modafinil to “Cure” Hangovers

The “Modafinil hangover remedy” we’re going to provide is more than just popping a white tablet and hoping for the best.

It entails treating every symptom of an alcohol-induced hangover, from the moment you wake up. To create this procedure, we merged scientific study with the personal experiences of hundreds of Modafinil users.

Without further ado, here is our complete method for successfully mixing Modafinil with hangovers…

  • Get Some Additional Sleep

Hangovers are less severe in those who obtain as much sleep as possible. Because sleep quality is inevitably diminished after ingesting big quantities of alcohol [8,] we highly advocate a minimum of 7 hours.

Setting an alarm is also not recommended. Whether or whether you plan to take Modafinil when you get up, you should be waking up naturally.

  • Long and pleasant shower

Physical activity is the most crucial factor in overcoming a hangover. Getting out of bed and into the shower will guarantee that your day gets off to a good start.

A hot shower, a cold shower, or a contrast shower are all options. Whichever one makes you most awake. Bathing yourself for 10-20 minutes should enough.

  • Keep Yourself Hydrated


Due to the dehydrating effects of alcohol, you should increase your fluid intake on the day of the hangover. More water will speed up the process of your body processing the leftover alcohol.

We suggest drinking at least one gallon (4 liters) of water throughout the day. Drink 20 ounces (0.5 liters) of water first thing in the morning.

On a side note, it’s a good idea to drink more water on the night you’re drinking — at least 1 glass of water each glass of alcohol.

  • Breakfast Should Be Big and Hearty

You should have your first meal of the day as soon as you wake up, in addition to rehydrating yourself.

This meal should be substantial, concentrating on the minerals, vitamins, and electrolytes lost by alcohol use.

In terms of particular foods, this advice is largely subjective, although widely advised dietary options include [9]:

  • Eggs
  • Avocado
  • Spinach and other dark leafy greens
  • Pickles
  • Meat
  • Oatmeal
  • Potatoes dulces
  • Blueberries
  • Soup with chicken noodles

Load up on complex carbs, high-protein meals, and healthy fat sources, and you won’t go wrong.

  • Electrolyte Supplementation

Electrolytes such as magnesium, potassium, and sodium are all decreased by alcohol intake. This is significant since low electrolyte levels may produce symptoms including weariness and disorientation [10].

As a result, you should eat electrolytes both at the start of the day and throughout the day to maintain an ideal electrolyte balance in your body.

Coconut water, Pedialyte, or Gatorade are our personal suggestions for electrolyte-dense sources, since all three have been demonstrated to be excellent at rehydrating. Coconut water, on the other hand, may be consumed in higher quantities without producing stomach distress [11].

  • Modafinil (modafinil) (200 mg)

It’s now time to utilize the “Modafinil hangover cure” now that you’re fully awake, well-hydrated, and well-fed.

We’re trying to overcome the lethargy and exhaustion brought on by the hangover, thus 200 mg is the upper limit of an optimal Modafinil dose.

  • Start Being Productive Right Now

Right after you Modafinil (modafinil) (200 mg), start working on an important task immediately. Some users like to have an espresso at their side while working for an extra boost in productivity.

If you’ve done everything perfectly up until this point, you should be able to work for 8-12 hours without becoming fatigued or needing to take a break.

  • Before going to bed, one last meal

We propose that your final meal of the day be as substantial as your first.

You don’t want to go to bed hungry since Modafinil suppresses your appetite. A bigger dinner can help you fall asleep faster [12], allowing you to wake up feeling refreshed the following morning.


Take care!

Despite the fact that Modafinil and hangovers may coexist, there are still measures to follow.

First and foremost, keep in mind that no official scientific research on the interaction of Modafinil and alcohol have been conducted.

While medication interactions are often examined, little is known about how Modafinil affects the body’s ability to clean down toxins after a night of binge drinking.

In truth, we only know that taking both medications at the same time is not recommended by the official product monograph [13]:

“Patients should be informed that PROVIGIL has not been investigated in conjunction with alcohol.” Patients should be informed that drinking alcohol should be avoided when taking PROVIGIL.”

Second, combining a potent CNS stimulant (Modafinil) with a powerful CNS depressive puts your health at danger (alcohol).

Everyone reacts differently, and the outcome is completely unexpected [14, 15]:

“Mixing stimulants and depressants puts the body under a tremendous amount of stress. With simultaneous confused instructions to accelerate up and calm down, the cardiovascular, respiratory, and central neurological systems are thrown into a frenzy.”

“The combined effects reduce the severity of each substance’s symptoms, giving the impression that the individual is not as inebriated as they are… Downers may cover a dangerously rapid pulse, while uppers may mask warning indications of deep CNS depression.”

Third, dehydration and nausea [16], which are also induced by a hangover, are two of the most prevalent Modafinil adverse effects.

Even if you are drinking more water than usual, Modafinil may exacerbate the dehydration you are suffering as a result of your hangover.

In summary, the “Modafinil hangover cure” should only be used as a last resort, not as a cover for difficulties caused by excessive drinking and/or alcohol addiction.

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User Interactions

What do other smart drug users have to say about Modafinil and hangovers on the internet?

Unfortunately, there are few anecdotal accounts of Modafinil being used to treat hangovers. Its efficacy seems to be mediocre at best.

Some people swear by Modafinil to help them avoid the harmful consequences of a hangover [17, 18]:

“I use modafinil as needed for school work a couple times a week.” When I take it after a night of heavy drinking, my hangover the following day is much minimized. I may wake up with a pounding headache and a general dislike of life, but after a half-hour on modafinil, I’m aware and typically in a good mood.”

“A day after moderate drinking, it permits me to be tremendously productive.” It would be a waste of time without it.”

Other users allege the reverse effect, claiming that Modafinil exacerbated their hangovers, which is grounds for concern [19, 20]:

“My hangover appeared to become worse after taking 100mg Modalert. I wouldn’t say anything you couldn’t handle, but it’s not a hangover you want to be dealing with at work. My tongue seems drier than normal, and my stomach is a touch queezy… This may have been an isolated incident in my situation, but I would not advocate using moda if you are hungover.”

“So I went about my day with a hangover, and the modafinil (100 mg) did its work and kept me up.” Things were going well until the headache hit [three hours later], which was bearable. It grew a lot worse once I went home, and I haven’t been able to do anything since.”

If Modafinil is being used to treat a hangover, users in both circumstances advised taking no more than 50mg.

At the end of the day, you’ll have to try our advised “Modafinil hangover cure” to see whether it works for you. It could work for some people while making a little impact for others.


Hangovers and Modafinil | Conclusion

Is it safe to combine Modafinil with hangovers?

A tiny quantity of research implies that a Modafinil hangover cure is conceivable and maybe beneficial. For the greatest outcomes, however, Modafinil must be combined with other healthy habits such as sleep, water, and diet.

At the absolute least, you may avoid falling behind on crucial work by a whole day by reducing the productivity-killing consequences of heavy alcohol intake.

Please don’t do this on a regular basis Because binge drinking and hangovers are dangerous to your health!

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  1. Modafinil. ncbi.nlm.nih.gov (accessed August 21, 2020).
  2. U. Müller, J.B. Rowe, T. Rittman, C. Lewis, T.W. Robbins, and B.J. Sahakian. In healthy volunteers, the effects of modafinil on nonverbal cognition, task pleasure, and creative thinking. Neuropharmacology 64(5):490-495, 2013. doi:10.1016/j.neuropharm.2012.07.009

  3. Are There Hangovers in Alcoholics? rehabcenter.net, retrieved August 23, 2020
  4. The Liver and Alcohol addictioncenter.com (accessed August 23, 2020).
  5. The Drugs of Wall Street. businessinsider.com, retrieved 17 August 2020.
  6. Specific therapy of residual tiredness in depressed individuals, Marin H, Menza MA. Psychiatry (Edgmont) 1(2):12-18, 2004.
  7. Modafinil may aid in the reduction of drinking in certain persons by enhancing impulse control. news-medical.net, retrieved August 22, 2020
  8. LE Devenney, KB Coyle, T Roth, JC Verster. Sleep after heavy alcohol consumption and levels of physical activity during an alcohol hangover 8(5):752 in J Clin Med. Published on May 27, 2019. doi:10.3390/jcm8050752
  9. The 23 Best Foods for a Hangover healthline.com, retrieved August 21, 2020
  10. Imbalance of electrolytes. healthgrades.com, retrieved August 22, 2020
  11. M. Saat, R. Singh, R. G. Sirisinghe, and M. Nawawi. Rehydrate with fresh young coconut water, carbohydrate-electrolyte beverage, and plain water after exercise. 2002;21(2):93-104 in J Physiol Anthropol Appl Human Sci. doi:10.2114/jpa.21.93

  12. Falling asleep after a heavy meal: Neuronal modulation of fullness, Gallagher T, You YJ. Worm. 2014;3:e27938. doi:10.4161/worm.27938. Published on January 31, 2014.
  13. [C-IV] PROVIGIL® (modafinil) Tablets The date is August 20, 2020. accessdata.fda.gov
  14. RISKS OF COMBINING STIMULANTS AND DEPRESSANTS. blackbearrehab.com (accessed August 23, 2020).
  15. The Hazards of Mixing Uppers and Lowers rbsrehab.com (accessed August 24, 2020).
  16. Modafinil. drugs.com (accessed August 20, 2020).
  17. My go-to hangover remedy is modafinil. The date is August 22, 2020. r/Drugs
  18. Is it effective in treating hangovers? The date is August 22, 2020. r/modafinil
  19. Modafinil Don’t do it if you’re hungry. The date is August 22, 2020. r/afinil
  20. Modafinil or hangover headache? The date is August 22, 2020. r/afinil



Modafinil is a drug that has been used for decades to help people stay awake and alert. However, the side effects of modafinil can include headaches. This article will discuss how to avoid or minimize the headache that comes with using this drug. Reference: modafinil headache.

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About the Author P. Tardner

Paul Tardner is the Head Writer at IJEST.org. Paul is a former academic and research scientist. He now dedicates his time to his own research into nootropics, with a particular focus on cognitive enhancement in old age. You can learn more about Paul from his profile page.