Sublingual Modafinil | Review of Benefits, Side Effects, & More

Modafinil is a prescription-only drug that can improve alertness and focus, making it an ideal tool for those who want to achieve their best performance. However, the effects of this medication may not be worth the side effects that come with long term use since many individuals stop using it after experiencing withdrawal symptoms.

Sublingual Modafinil | Review of Benefits, Side Effects, & More

Are you unsure about sublingual modafinil? You are most certainly not alone.

It’s a special kind of modafinil that’s taken sublingually (under the tongue) rather than eaten like a tablet.

Although there are various advantages to taking medicines sublingually, many doubts remain concerning whether sublingual modafinil is worth purchasing.

Here’s everything we know about sublingual modafinil, including its benefits and drawbacks, as well as where to acquire it.

 

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What Is Modafinil Sublingual?

Sublingual modafinil, as previously stated, is a type of the medication modafinil that is dissolved beneath the tongue rather than eaten like the tablet form.

Modafinil is a prescription drug that was created to treat a variety of sleep problems, including sleep apnea, narcolepsy, and shift work sleep disorder. It’s intended to assist these folks stay awake and attentive throughout the day, or during their working hours in the case of shift workers [1, 2].

Doctors, on the other hand, recommend medication to aid with exhaustion caused by a variety of medical diseases (multiple sclerosis and depression, for instance). It has several cognitive advantages in addition to energy as a wakefulness agent, such as increased attention and concentration. As a result, it’s often used to treat attention deficit hyperactivity disorder (ADHD). It’s also a popular nootropic, or “smart drug,” with many nootropics users reporting that it improves their ability to concentrate, remember information, and get more done in their day [3, 4].

 

Modafinil sublingual vs. Provigil

Cephalon Labs manufactures Provigil, the original modafinil. It’s a 200 mg oral pill that may be divided in half if required.

Several generic variants of modafinil have been brought to the market since generics were first made accessible. While many of them are very similar to Provigil, several also come in 100 mg tablet form.

However, it seems that Modafil MD is the only modafinil generic having a sublingual method of administration. It’s available in 100 mg and 200 mg pills that are meant to be dissolved under the tongue rather than eaten.

Because they all include the same active ingredient (modafinil), all of these diverse formulas and brands should theoretically provide the same benefits; however, this hasn’t been our experience, and it doesn’t match what other nootropics users have reported. Some generic modafinil products just appear to work better than others.

 

Modafinil Sublingual Benefits

Modafinil has been linked to a number of nootropic advantages. Here are several that match current studies on modafinil and its effects on the brain:

  • More vitality. Modafinil has been shown in many trials to assist patients with a variety of diseases, including depression and multiple sclerosis, feel less tired. It’s also been used to keep awake and alert combat pilots who are sleep deprived but otherwise healthy. Many users claim that modafinil helps them remain alert throughout the day without feeling buzzing or jittery – and with no crash [5, 6, 7].
  • Improved memory, focus, and decision-making abilities. Participants in a research of healthy individuals concluded that a single dosage of 200 mg modafinil enhanced memory, pattern identification, planning, and decision making. Many persons who use modafinil for its nootropic effects say that these benefits are more important to them than the improved energy — they want to improve their attention [8].
  • Mood has improved. Modafinil may be a suitable adjunct to established therapy like counseling and medicine in depressed patients. Modafinil improved depressive symptoms in persons with major depression and bipolar depression, according to a review of studies [9].

Unfortunately, there is less proof of modafinil’s brain-enhancing benefits in healthy persons. However, according to one study, several research looking at the effects of modafinil on healthy individuals have shown that it increases executive functioning (decision making), attention, learning, and memory – with little side effects or mood changes. Although additional study on the cognitive enhancing potential of modafinil in otherwise healthy persons is needed, our personal experience and anecdotal accounts from nootropics users support this [10].

Additionally, there are various advantages of administering medications sublingually. Here are a few ways it differs from the typical method of administration, which involves swallowing a pill.

Sublingual medication delivery reduces pill burden for those who take a lot of pills on a daily basis and gives an alternate route of administration for persons who have difficulty swallowing pills. However, one of the most intriguing advantages of sublingual medications is that they are absorbed straight into the circulation [11].

Traditional tablets must transit through the whole digestive system before being taken to the liver, where their composition might be drastically altered during liver metabolism. The “first pass effect” is a phenomenon that occurs with numerous medications [12, 13].

Sublingual medications, on the other hand, are absorbed straight into the circulation, bypassing digestion and liver metabolism, allowing them to take action faster and be more effective than the same quantity of drug given in tablet form.

Unfortunately, no actual study on sublingual modafinil has been done, so we can’t tell for sure if it has any advantages over the tablet version. In fact, nootropics users who have used sublingual modafinil in the past — who are few and far between — are generally unhappy with it and prefer alternative kinds of modafinil.

 

Modafinil Sublingual Side Effects

Sublingual modafinil, like the original brand Provigil and other generic equivalents, has a long list of possible adverse effects. According to the United States National Library of Medicine [2], the following are the most prevalent modafinil side effects:

  • “headache
  • dizziness
  • Having trouble falling or staying asleep
  • drowsiness
  • nausea
  • diarrhea
  • constipation
  • gas
  • heartburn
  • appetite suppression
  • odd flavors
  • mouth is dry
  • extreme thirst
  • nosebleed
  • flushing
  • sweating
  • muscular tension or difficulty moving
  • backache
  • confusion
  • a section of your body shakes uncontrollably
  • Skin that is scorching, tingling, or numb
  • “Difficulty seeing or discomfort in the eyes”

They further state that the following serious side effects need immediate medical attention:

  • “rash
  • blisters
  • skin peeling
  • mouth ulcers
  • hives
  • itching
  • hoarseness
  • breathing or swallowing problems
  • Face, neck, tongue, lips, eyes, hands, feet, ankles, and lower legs swelling
  • chest discomfort
  • pulse that is rapid, hammering, or irregular
  • a frantic, unusually eager mood
  • having hallucinations (seeing things or hearing voices that do not exist)
  • anxiety
  • depression
  • “considering suicide or injuring oneself”

The most typical adverse effect of modafinil usage, according to our experience and what others have mentioned in forums, is headaches. If you’ve been suffering with modafinil headaches, we’ve put up a guide to assist you get rid of them.

Sublingual modafinil has the unwanted side effect of producing unpleasant body odor. Sublingual Modafinil, according to two Reddit users, caused them stink or made their perspiration smell awful. According to what we’ve heard and read, this adverse effect isn’t common with the tablet version of modafinil, therefore it might be tied to the sublingual way of administration.

 

Where Can I Buy Modafinil Sublingual Online? | 2022 Guide

Are you looking to buy sublingual modafinil? Modafinil XL is a merchant that we suggest. Modafil MD, the sole brand of sublingual modafinil on the market, is available in 100 mg and 200 mg dosages. It costs roughly $1 per tablet, however the price per tablet is reduced in bigger numbers.

Modafinil XL is one of our favorite companies since they ship internationally, utilize quality packaging, and provide a variety of payment methods. Free standard delivery is available with a $80 purchase, and free express shipping is available with a $180 purchase. If you pay using Bitcoin, you can also earn a 20% discount on your total transaction.

Finally, they’re known in the internet nootropics community for being a trustworthy organization.

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Is Modafinil Sublingual Legal?

The legality of modafinil (and hence sublingual modafinil) varies by location. For example, it’s a legitimate Schedule IV prescription medicine in the United States, which means it has a minimal risk of misuse. In the United Kingdom, it is also a legal prescription medicine [14].

Make sure you know whether modafinil is legal in your country before buying it online.

We have yet to hear of a single example in the United States of an individual suffering legal consequences for purchasing modafinil for personal use online.

 

How Long Does Modafinil Work When Taken Sublingually?

Unfortunately, since we know so little about sublingual modafinil, this is a difficult issue to address. There aren’t many reports online regarding it since it’s not extensively utilized by nootropics fans.

The effects of modafinil in tablet form are usually felt 1-2 hours after administration, according to most users.

Because sublingual modafinil enters the circulation immediately, it should be felt sooner than the tablet form [15].

However, among the few individuals who have tried it and published their experiences online, this does not seem to be the case.

Many users on online nootropics communities claim to prefer alternative modafinil generics, such as Modalert and Modvigil.

 

Modafinil Sublingual Dosage and Tolerance

Modafinil is available in two dosages: 100 mg and 200 mg. Surprisingly, when purchasing greater amounts of Modafinil XL, the 200 mg pills are the least costly option.

The normal prescription dosage of modafinil for patients who require it to help them remain awake is 200 mg. Nootropics users, on the other hand, claim remarkable success with modafinil dosages ranging from 50 mg to 300 mg per day.

Fortunately, there’s little chance of abusing modafinil, and you’re unlikely to develop a tolerance to it.

When attempting a new nootropic — or even a different sort of modafinil — it’s essential to be careful, in our opinion. We find it best to begin with the smallest amount possible, carefully evaluating our response to the treatment, and adjusting dosage as needed.

 

Modafinill vs. Modalert vs. Modvigil vs. Provigil (sublingual)

If you’ve looked into Modafinil XL, you may be surprised at how many distinct forms of modafinil are available. Should you go with the sublingual modafinil or something like Modalert, which is more popular among nootropics users?

We advocate the latter for many reasons, but first, let’s go through some of the most frequent modafinil types:

  • Cephalon Labs’ Provigil is the brand name for modafinil. It’s not well-known among nootropics users.
  • Modalert is one of numerous different forms of generic modafinil. It seems to be the most powerful in terms of brain-enhancing benefits, based on our experience and user reviews on Reddit and nootropics sites.
  • Modvigil is a generic version of Modafinil, similar to Modalert. It is popular among nootropics users since it is the least priced form while still being effective.

We prefer Modalert and Modvigil above all other modafinil products, including name brand Provigil and sublingual Modafil MD. They’re both extensively utilized by nootropics consumers and are simple to get on Modafinil XL. Their makers have a longer track record and have a higher reputation than some other modafinil producers.

Finally, while possessing the same quantity of active component, several users have stated that they seem to be more effective than other varieties of modafinil. This shows that alternative products may have quality control difficulties, leading us to believe that sticking with Modalert or Modvigil is the best choice.

 

Modafinil Sublingual Review: What’s the Bottom Line?

Sublingual modafinil is a form of modafinil that dissolves beneath your tongue instead of being swallowed like a tablet. Modafil MD, which can be purchased from Modafinil XL, is the only variety of sublingual modafinil on the market right now.

Sublingual drugs may reach the circulation immediately, skipping digestion and liver processing, which means they may be more potent than tablet versions of the same prescription. However, according on user feedback, this does not seem to be the case with Modafil MD.

We suggest sticking to other varieties of modafinil, such as Modalert or Modvigil, unless you require sublingual modafinil because you have difficulties swallowing tablets.

Modafinil may be purchased online from one of the greatest providers in the globe.

Prices are reasonable, shipment is rapid, and arrival is guaranteed.

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References

  1. Sleep Med Clin. 2020;15(2):177-194. doi:10.1016/j.jsmc.2020.02.006 Takenoshita S, Nishino S. Pharmacologic Management of Excessive Daytime Sleepiness.
  2. National Library of Medicine, United States. Modafinil. Website of MedlinePlus. 15 February 2016. https://medlineplus.gov/druginfo/meds/a602016.html
  3. RA Pealoza, U Sarkar, DM Claman, and TA Omachi. In a nationally representative population, trends in on-label and off-label modafinil usage were examined. 704-706 in JAMA Intern Med, 2013. doi:10.1001/jamainternmed.2013.2807
  4. W. Wilms, M. Woniak-Karczewska, P. F. Corvini, and P. F. Chrzanowski. Methylphenidate, modafinil, and piracetam: A study of population usage trends, environmental occurrence, ecotoxicity, and removal strategies. 233:771-785 in Chemosphere. doi:10.1016/j.chemosphere.2019.06.016
  5. P. Videbech, P. Videbech, P. Videbech, P. Videbech, P. Videbech, P. Videbech, P. Videbech, P. Videbech, P. Videbech, P. Videbech,
  6. Modafinil for the treatment of multiple sclerosis-related tiredness, Brown JN, Howard CA, Kemp DW. 1098-1103. doi:10.1345/aph.1M705. Ann Pharmacother. 2010;44(6):1098-1103.
  7. Modafinil’s impact on simulator performance and mood in pilots after 37 hours without sleep, Caldwell JA, Caldwell JL, Smith JK, Brown DL. 2004;75(9):777-784 in Aviat Space Environ Med.
  8. U. Müller, J.B. Rowe, T. Rittman, C. Lewis, T.W. Robbins, and B.J. Sahakian. In healthy volunteers, the effects of modafinil on nonverbal cognition, task pleasure, and creative thinking. Neuropharmacology 64(5):490-495, 2013. doi:10.1016/j.neuropharm.2012.07.009
  9. AJ Goss, M Kaser, SG Costafreda, BJ Sahakian, and CH Fu. A comprehensive review and meta-analysis of randomized controlled trials of modafinil augmentation treatment in unipolar and bipolar depression. 74(11):1101-1107 in J Clin Psychiatry, 2013. doi:10.4088/JCP.13r08560
  10. Modafinil for cognitive neuroenhancement in healthy non-sleep-deprived subjects: A comprehensive review, Battleday RM, Brem AK. doi:10.1016/j.euroneuro.2015.07.028. Eur Neuropsychopharmacol. 2015;25(11):1865-1881.
  11. Shader RI. Polypharmacy, Pill Burden, and Medicine Cabinet Optimization. doi:10.1016/j.clinthera.2019.11.002 Clin Ther. 2019;41(12):2461-2462
  12. The First Pass Effect, by TF Herman and C Santos. StatPearls Publishing, Treasure Island (FL), September 3, 2020.
  13. Sublingual tablets and the advantages of the sublingual mode of administration, Khan AB, Kingsley T, Caroline P. 2017;16(3):257-267 in J Pharm Res. doi:10.18579/jpcrkc/2017/16/3/118766
  14. Justice Department. Modafinil has been classified as a Schedule IV restricted drug. The date was January 27, 1999. https://www.deadiversion.usdoj.gov/fed regs/rules/1999/fr0127.htm
  15. Sublingual medication delivery: an indicator of a possible alternative route, Saha P, Verma S, Das PS. doi:10.22159/ijcpr.2017v9i6.23436

 

 

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About P. Tardner

Paul Tardner is the Lead Author at IJEST.org. Paul is a former academic and research scientists. He now dedicates his time to his own research into natural biohacking, with a particular focus on cognitive enhancement.

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